Coding
Part:BBa_K3142007:Design
Designed by: Luo Xiaolin Group: iGEM19_SZPT-CHINA (2019-10-13)
Milk-derived antihypertensive tripeptide(VPP)
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
The sequence has been optimized for lactic acid bacteria. It is a small molecule bioactive peptide that is difficult to directly biosynthesize. Therefore, the fusion expression strategy is currently used.
Source
no
References
Nakano, D., K. Ogura, M. Miyakoshi, F. Ishii, et, al. Antihypertensive effect of angiotensin I-converting enzyme inhibitory peptides from a sesame protein hydrolysate in spontaneously hypertensive rats. [J] Biosci Biotechnol Biochem 2006, 70:1118–1126.